Lancet Latest Research

Lancet (London, England)22/09/2026

Peripheral arterial disease: adverse impacts, disparities in outcomes, and the path ahead.

Lancet (London, England)22/09/2026

Understanding peripheral arterial disease in the current era.

Lancet (London, England)22/09/2026

Current advancements in the care of peripheral arterial disease: modern approaches to medical, endovascular, and surgical treatment.

Lancet (London, England)12/09/2026

Efficacy and safety of mitapivat in adults with transfusion-dependent α-thalassaemia or β-thalassaemia (ENERGIZE-T): a double-blind, randomised, multicentre, placebo-controlled, phase 3 trial.

Lancet (London, England)12/09/2026

Mitapivat for transfusion-dependent α-thalassaemia and β-thalassaemia.

Lancet (London, England)09/09/2026

Perioperative immunotherapy goes global in gastro-oesophageal cancer.

Lancet (London, England)09/09/2026

Perioperative durvalumab plus fluorouracil, leucovorin, oxaliplatin, and docetaxel for resectable gastric and gastro-oesophageal junction adenocarcinoma (MATTERHORN): final results of overall survival and event-free survival by pathological response in a global, randomised, double-blind, placebo-controlled, multicentre, phase 3 trial.

Lancet (London, England)08/09/2026

Wildfire smoke and health: current evidence, mechanisms, and future challenges.

Lancet (London, England)07/09/2026

Use of the bacterial lysate OM-85 for the primary prevention of wheezing lower respiratory illness in preschool children: a randomised, placebo-controlled trial.

Lancet (London, England)06/09/2026

Induction and consolidation atezolizumab with stereotactic body radiation therapy versus radiation alone in high-risk, early-stage non-small-cell lung cancer (SWOG/NRG S1914): a multicentre, open-label, superiority, phase 3, randomised controlled trial.

Lancet (London, England)06/09/2026

The changing therapeutic landscape of small-cell lung cancer.

Lancet (London, England)05/09/2026

Liposuction versus conservative therapy for patients with lipoedema in Germany: a multicentre, randomised controlled clinical trial.

Lancet (London, England)03/09/2026

Natural history and clinical impact of epilepsy in adults with Down syndrome: a multicentre clinical study.

Lancet (London, England)03/09/2026

Porcine kidney xenotransplantation as a bridge to allotransplantation: a first-in-human study.

Lancet24/06/2026

Efficacy and safety of tirofiban after successful endovascular reperfusion in acute ischaemic stroke (ATTRACTION) in China: a multicentre, double-blind, randomised controlled trial.

Lancet12/07/2025

Cerebral palsy.

Lancet04/01/2025

Osteoarthritis.

Lancet10/08/2024

Activity limitations, use of assistive devices, and mortality and clinical events in 25 high-income, middle-income, and low-income countries: an analysis of the PURE study.

Lancet13/07/2024

Effectiveness and cost-effectiveness of an individualised, progressive walking and education intervention for the prevention of low back pain recurrence in Australia (WalkBack): a randomised controlled trial.

Lancet30/03/2024

Telerehabilitation consultations with a physiotherapist for chronic knee pain versus in-person consultations in Australia: the PEAK non-inferiority randomised controlled trial.

Lancet20/01/2024

Medical, surgical, and physical treatments for Parkinson's disease.

LancetNov 2023

Better informing everyday fall risk assessment: experimental studies with contemporary technologies.

LancetNov 2023

Gait retraining to reduce falls: an experimental study toward scalable and personalised use in the home.

LancetNov 2023

Trajectories of depressive symptoms 10 years after stroke and associated risk factors: a prospective cohort study.

Lancet03/06/2023

Cognitive functional therapy with or without movement sensor biofeedback versus usual care for chronic, disabling low back pain (RESTORE): a randomised, controlled, three-arm, parallel group, phase 3, clinical trial.

Lancet05/11/2022

Intensive blood pressure control after endovascular thrombectomy for acute ischaemic stroke (ENCHANTED2/MT): a multicentre, open-label, blinded-endpoint, randomised controlled trial.

Lancet10/09/2022

Metabolic, behavioural, and psychosocial risk factors and cardiovascular disease in women compared with men in 21 high-income, middle-income, and low-income countries: an analysis of the PURE study.

Lancet14/05/2022

Long-term secondary prevention of cardiovascular disease with a Mediterranean diet and a low-fat diet (CORDIOPREV): a randomised controlled trial.

Lancet03/07/2021

Low back pain.

Lancet12/06/2021

Parkinson's disease.

Lancet24/04/2021

Vagus nerve stimulation paired with rehabilitation for upper limb motor function after ischaemic stroke (VNS-REHAB): a randomised, blinded, pivotal, device trial.

Lancet06/03/2021

Diagnosis of non-consensus transient ischaemic attacks with focal, negative, and non-progressive symptoms: population-based validation by investigation and prognosis.

Lancet03/10/2020

Management of adults with primary frozen shoulder in secondary care (UK FROST): a multicentre, pragmatic, three-arm, superiority randomised clinical trial.

Lancet17/08/2019

Expanding traditional tendon-based techniques with nerve transfers for the restoration of upper limb function in tetraplegia: a prospective case series.

Lancet09/03/2019

Prehospital transdermal glyceryl trinitrate in patients with ultra-acute presumed stroke (RIGHT-2): an ambulance-based, randomised, sham-controlled, blinded, phase 3 trial.

Lancet22/09/2018

Use of aspirin to reduce risk of initial vascular events in patients at moderate risk of cardiovascular disease (ARRIVE): a randomised, double-blind, placebo-controlled trial.

Lancet08/09/2018

Radial versus femoral access and bivalirudin versus unfractionated heparin in invasively managed patients with acute coronary syndrome (MATRIX): final 1-year results of a multicentre, randomised controlled trial.

Lancet26/05/2018

Tranexamic acid for hyperacute primary IntraCerebral Haemorrhage (TICH-2): an international randomised, placebo-controlled, phase 3 superiority trial.

Lancet27/01/2018

Arthroscopic subacromial decompression for subacromial shoulder pain (CSAW): a multicentre, pragmatic, parallel group, placebo-controlled, three-group, randomised surgical trial.

Lancet15/04/2017

Intensive speech and language therapy in patients with chronic aphasia after stroke: a randomised, open-label, blinded-endpoint, controlled trial in a health-care setting.

LancetApr 2017

Evolving concepts in the treatment of relapsing multiple sclerosis.

Lancet18/02/2017

Non-specific low back pain.

Lancet17/09/2016

Addition of a non-immersive virtual reality component to treadmill training to reduce fall risk in older adults (V-TIME): a randomised controlled trial.

Lancet14/11/2015

Alcohol consumption and cardiovascular disease, cancer, injury, admission to hospital, and mortality: a prospective cohort study.

Lancet31/10/2015

Long working hours and risk of coronary heart disease and stroke: a systematic review and meta-analysis of published and unpublished data for 603,838 individuals.

Lancet04/07/2015

Efficacy and safety of very early mobilisation within 24 h of stroke onset (AVERT): a randomised controlled trial.

Lancet07/02/2015

Long-term outcomes after stenting versus endarterectomy for treatment of symptomatic carotid stenosis: the International Carotid Stenting Study (ICSS) randomised trial.

Lancet (London, England)21/10/2010

Efficacy and safety of corticosteroid injections and other injections for management of tendinopathy: a systematic review of randomised controlled trials.

Lancet

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