Osteoarthritis and Cartilage

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• Reply to the letter to the editor concerning: T mapping of the articular cartilage as a biomarker for knee osteoarthritis: An analysis of the population-based Rotterdam Study.

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  Osteoarthritis and Cartilage · 2025
• Rethinking mitochondria in scRNAseq analysis.

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  Osteoarthritis and Cartilage · 2025
• Physiotherapist-led weight management for people with osteoarthritis: A scoping review.

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  Osteoarthritis and Cartilage · 2025
• Imeglimin, a novel antidiabetic agent related to metformin, attenuates knee osteoarthritis development and progression through AMPK activation and NF-κB signaling inhibition.

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  Osteoarthritis and Cartilage · 2025
• Response to letter to the editor regarding 'The relation of walking forces to structural damage in the knee: The Multicenter Osteoarthritis Study'.

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  Osteoarthritis and Cartilage · 2025
• Transcriptomic profiling confirms microRNA-140 is more functional in joint development than in disease.

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  Osteoarthritis and Cartilage · 2025
• Osteoarthritis year in review 2025: Imaging.

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  Osteoarthritis and Cartilage · 2025
• Uncovering causal genetic mediators linking redefined obesity to osteoarthritis: Multidimensional analysis from population to genetic mechanisms.

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  Osteoarthritis and Cartilage · 2025
• Usefulness of 3D joint space width on weight-bearing CT in comparison with 2D joint space width on radiographs for predicting 24-month worsening of knee osteoarthritis pain and function in the MOST study.

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  Osteoarthritis and Cartilage · 2025
• The impact of screening period pain inconsistency on placebo response in intra-articular knee osteoarthritis trials.

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  Osteoarthritis and Cartilage · 2025
• Tribological impact of synovial fluid alterations in osteoarthritis: Correlation analyses between cartilage friction and synovial fluid properties.

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  Osteoarthritis and Cartilage · 2025
• The burden of osteoarthritis: Lifespan matters.

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  Osteoarthritis and Cartilage · 2025
• Association of ligament mechanical properties and articular surface topography with trapeziometacarpal kinematics across osteoarthritis stages.

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  Osteoarthritis and Cartilage · 2025
• Letter to the Editor concerning: T mapping of the articular cartilage as a biomarker for knee osteoarthritis: An analysis of the population-based Rotterdam Study.

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  Osteoarthritis and Cartilage · 2025
• Response to the Letter to the Editor: Effects of pre- and postsurgery physical activity interventions on physical activity and sedentary behavior levels following knee and hip arthroplasty: A systematic review and meta-analysis of randomized controlled trials.

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  Osteoarthritis and Cartilage · 2025
• Intersectional racial, ethnic, and sex-based disparities in length of stay after total hip and knee arthroplasty: An analysis of national data.

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  Osteoarthritis and Cartilage · 2025
• Using both disease and illness as outcomes is critical in OA prevention research.

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  Osteoarthritis and Cartilage · 2025
• Why is there no treatment for osteoarthritis - Opportunity for AI based big data analytics to advance the field.

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  Osteoarthritis and Cartilage · 2025
• Why most responder analyses are misleading.

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  Osteoarthritis and Cartilage · 2025
• Sex Differences in Preoperative Pain Intensity Among Patients Undergoing Total Knee Arthroplasty: A Propensity Score-Matched Cross-Sectional Study.

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  Osteoarthritis and Cartilage · 2025
• Metformin and incident osteoarthritis: Causal insights from a co-twin control study.

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  Osteoarthritis and Cartilage · 2025
• Comprehensive Zonal Assessment of Meniscal Degeneration Using Quantitative UTE MRI.

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  Osteoarthritis and Cartilage · 2025
• Mobile app to support home exercise adherence in knee osteoarthritis: A randomized clinical trial.

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  Osteoarthritis and Cartilage · 2025
• Osteoarthritis year in review 2025: Biology.

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  Osteoarthritis and Cartilage · 2025
• Engineered Cationic Interleukin-1 Receptor Antagonist Outperforms Anakinra at Joint Retention and Preventing IL-1-induced Cartilage Inflammation.

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  Osteoarthritis and Cartilage · 2025
• The smallest worthwhile effects of strengthening exercise on pain intensity for people with knee osteoarthritis: A benefit-harm trade-off study.

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  Osteoarthritis and Cartilage · 2025
• Immediate reductions in compressive and shear forces in the knee from gait retraining are associated with slowed cartilage degeneration after 1 year in medial knee osteoarthritis: A retrospective observational cohort study.

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  Osteoarthritis and Cartilage · 2025
• Sympathosensory interactions - Possible relevance in osteoarthritis.

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  Osteoarthritis and Cartilage · 2025
• Does spontaneous cartilage thickening occur in osteoarthritic knees? Data from IMI-APPROACH and the OAI.

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  Osteoarthritis and Cartilage · 2025
• Unicompartmental versus bicompartmental joint space width measures: Which reflect whole joint structural damage better? Data from IMI-APPROACH.

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  Osteoarthritis and Cartilage · 2025
• E1K, a disease-modifying drug candidate for knee osteoarthritis, alleviates pain and regenerates cartilage simultaneously by inhibiting TGF-β1-mediated SMAD1/5/9 signaling in osteoarthritis models.

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  Osteoarthritis and Cartilage · 2025
• Excessive compression induces cartilage endplate degeneration via the Piezo1/NAT10/mTOR signaling axis.

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  Osteoarthritis and Cartilage · 2025
• Tribute to Dr. Frank Beier (1965-2025).

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  Osteoarthritis and Cartilage · 2025
• Quantitative MRI Assessment of Knee Cartilage Alterations Following 60-Day Head-Down Bed Rest.

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  Osteoarthritis and Cartilage · 2025
• Reframing Early-stage Symptomatic Knee Osteoarthritis (EsSKOA): A Strategic Lens for Trial Design.

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  Osteoarthritis and Cartilage · 2025
• Preventing osteoarthritis after anterior cruciate ligament injury: The case for targeting pre-osteoarthritis illness.

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  Osteoarthritis and Cartilage · 2025
• Observations of early structural changes over 6 years on magnetic resonance imaging in knees without radiographic osteoarthritis.

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  Osteoarthritis and Cartilage · 2025